Increasingly, direct genetic testing for germline mutations in the BRCA1 and BRCA2 genes is used to identify patients at risk for hereditary breast and ovarian cancer (HBOC). Genetic testing for germline mutations in BRCA1 and BRCA2 is indicated for:
- Individuals with a personal or family history of breast cancer before age 50 or ovarian cancer at any age
- Individuals with two or more primary diagnoses of breast and/or ovarian cancer
- Individuals of Ashkenazi Jewish descent with a personal or family history of breast cancer before age 50 or ovarian cancer at any age
- Male breast cancer patients
Genetic testing will allow you to accurately assess your patients' hereditary cancer risk and then adjust their management accordingly.
View mutation prevalence tables for BRCA1 and BRCA2 genes.
A genetic test for hereditary breast and
ovarian cancer
