|
Mutation Prevalence Tables
View Mutation Prevalence Tables  for BRCA1 and BRCA2 genes.
*Requires FREE Adobe Acrobat Reader
Lynch Syndrome Mutation Prevalence Table
|
The Prevalence of Deleterious Mutations in MLH1 or MSH2 (N=3410)
|
| |
Family History (Includes at least one first or second degree relative)
|
| Personal History |
No Affected Relatives |
> 1 Relative Affected |
| Colorectal Cancer <50 |
7.2% |
27.5% |
| Colorectal Cancer >50 |
4.4% |
14.1% |
| Endometrial Cancer <50 |
7.0%* |
29.9% |
| Other Lynch Syndrome Cancer |
3.6%** |
14.3% |
| >1 Lynch Syndrome Cancer |
8.8% |
45.8% |
|
* Estimate calculated according to PREMM12 model; Myriad's N<25.
** Myriad's N<50
Table Last Updated: November 2007
|
|
