Managing Patients with Hereditary Melanoma Syndrome
If the MELARIS® test shows an increased risk for melanoma and pancreatic cancer, the following medical management options may help reduce that risk.
Increased Surveillance
Skin:
- Monthly self-skin exams by patients beginning in childhood 75,81
- Clinical full-body skin exams every 6 to 12 months, beginning at age 10 74,75,81,82
- Baseline whole-body photography every 6 to 12 months beginning at age 10 76,82
Pancreas:
- Consider endoscopic ultrasound (EUS), computed tomography (CT), or endoscopic retrograde cholangiopancreatography (ERCP) OR
78,79,80,82
- Referral to research screening protocols
Preventive Surgery
- Immediate biopsy and/or removal of suspicious moles 75,77,82
Preventive Lifestyle Adjustments
- Limited exposure to the sun or ultraviolet radiation (e.g., tanning beds) 75,77,82
- Protective clothing, such as wide-brimmed hats, sunglasses, and long-sleeved shirts 75,77,82
- Application of sunscreen with a sun protection factor (SPF) of 15 or higher at regular intervals, especially in young children 75,77,82
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