The BRCA Risk Calculator is based on data, updated periodically, that represent observations of deleterious mutations by Myriad Genetic Laboratories through its clinical testing service. Data obtained through testing performed under specific research protocols is not included. The data were obtained from a routine laboratory requisition form and have not been independently verified by Myriad Genetic Laboratories. Patients for whom relevant information was not provided were not included in this tabulation. The data on Ashkenazi, or Eastern European Jewish ancestry are for patients tested only for 3 prevalent founder mutations as well as patients tested by full sequence analysis. The method used to develop the prevalence tables has been published in: Frank TS et al. Clinical Characteristics of Individuals with Germline Mutations in BRCA1 and BRCA2: Analysis of 10,000 Individuals.15 Please contact clinresearch@myriad.com or call 1-800-469-7423 with any questions or comments.
for BRCA1 and BRCA2 genes.
