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Benefits of Testing

COLARIS AP® can help you to understand if your family history of cancer is the result of either FAP, AFAP, or MAP. Knowing whether or not you have a polyposis syndrome, and identifying which one, guides decisions and actions that can help prevent cancer or detect it at an earlier, more treatable stage.

  • A positive result allows you to immediately help reduce your risk of a first or second cancer by earlier and more frequent screening strategies. In some cases risk may be eliminated through preventive surgery
  • A negative result rules out a common cause of hereditary colorectal cancer and may reduce worry about passing high risk onto children
  • Healthcare professionals can use the information to guide their plan for medical or surgical treatment
  • Results for one family member can give other members important information about their own level of risk


Limitations of Testing

  • Testing does not detect all causes of hereditary cancer
  • A negative result is most helpful when there is a known mutation in the family
  • Some variants are of unknown clinical significance

"I think having genetic testing has been beneficial in our situation. With the COLARIS AP® test, we already knew who was at (increased) risk in our family situation, and who wasn't."

— Jane, APC mutation positive for FAP

 

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